ChromoTek GmbH pioneers a new class of immunologic research tools derived from single domain camel antibodies for cell biology and proteomics. Founded in 2008 as a spin-off from the Ludwig-Maximilians University Munich (LMU), ChromoTek has rapidly developed to become a renowned supplier of innovative reagents
New tools for better research
ChromoTek's products center around the proprietary Chromobody® technology. For that, the innovative single domain camel antibody fragments are either coupled to a matrix (Nano-Traps), to a fluorescent dye (Booster) or fused to a fluorescent protein (Chromobodies®). Their extremely small size and high stability make them ideal reagents for biomolecular research and live cell assays.
Nano-Traps (e.g. GFP-Trap®, RFP-Trap®), are routinely used in labs all over the world to pulldown tagged proteins and interaction partners thereof from cell extracts, membrane or nuclear preparations. These recombinant binding proteins allow fast, efficient and reliable analytical and preparative one-step purification of proteins for a multitude of downstream applications (Western Blot, ChIP, Mass spec etc.).
Booster are useful to increase the fluorescence signal in essentially all microscopy applications by attaching a stable chemical fluorescent dye to green fluorescent or red fluorescent protein tags. Their advantage is to deliver enhanced sensitivity, especially in cases where photobleaching of samples is a problem.
In genetic fusion with a fluorescent protein, Chromobodies® are functional in living cells where they detect and visualize endogenous target structures in real time. We leverage this unique feature of Chromobodies® to bring high content, dynamic live cell imaging to a next level of performance.